Effects of host restriction factors and the HTLV-1 subtype on susceptibility to HTLV-1-associated myelopathy/tropical spastic paraparesis

Table 6 Characterization of TRM5α SNPs and proviral loads in HAM/TSP and ACs

AA change in TRIM5α	Minor allele frequency	HTLV-1 proviral loads (copies/10⁴ PBMC)
AA change in TRIM5α	Minor allele frequency	Minor allele	Major allele	p
H43Y	0.265	623 ± 894	606 ± 802	0.897
G110R	0.009	514 ± 344	612 ± 829	0.867
V112F	0.123	637 ± 790	608 ± 832	0.871
R136Q	0.137	354 ± 401	654 ± 870	0.003
H304L	0.014	1669 ± 1411	595 ± 809	0.025
F379 V	0.005	495	612 ± 828	NA

ISSN: 1742-4690