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Table 1 Comparison of HIV and HERV-K IC90 values for antiretroviral drugs

From: Inhibition of human endogenous retrovirus-K by antiretroviral drugs

Antiretroviral drugs HIV IC90 HERV-K IC90 (µM) HERV-K IC50 (µM)
Abacavir 2.3 µM 0.175 0.006
Zidovudine 0.03 µM 0.070 0.008
Darunavir 2.7–13 nM 0.071 0.029
Lopinavir IC50 17 nM (no serum)
IC50 102 nM (50% serum)
0.651 0.034
Raltegravir 0.033 µM 0.075 0.01