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Fig. 3 | Retrovirology

Fig. 3

From: Conserved residues within the HIV-1 Vpu transmembrane-proximal hinge region modulate BST2 binding and antagonism

Fig. 3

Hinge region E28/L33 residues are important for Vpu co-localization with BST2. a Representative pictures showing extent of co-localization of Vpu mutants with endogenous BST2 in HeLa cells as determined by the co-staining of anti-Vpu (green) and anti-BST2 (red) Abs following intracellular staining for both Vpu and BST2. b PCC values obtained from quantification of co-stainings of anti-Vpu and anti-BST2 Abs from at least 40 distinct transfected cells. The white bars in panel A represent a distance of 10 µm and the horizontal lines in panel B represent the mean PCC. Statistical analyses were performed using Mann–Whitney test

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