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Fig. 3 | Retrovirology

Fig. 3

From: DNA hypomethylation and aberrant expression of the human endogenous retrovirus ERVWE1/syncytin-1 in seminomas

Fig. 3

Expression analysis of the ERVFRDE1 locus. Expression from the ERVFRDE1 locus was analyzed by qRT-PCR in the panel of tumor samples. Both the full-length RNA (a) and spliced syncytin-2 mRNA (b) forms were quantified. All the data were normalized to % POLR2A. Each sample is represented by a dot and was measured as a technical triplicate. In each column, median with interquartile range is depicted. Splicing efficiency is shown in panel (c). Each sample is depicted by a dot which represents the ratio of spliced mRNA to the sum of full-length RNA and spliced mRNA in the analyzed sample. Significance was assigned as follows: **** for P-values <0.0001, *** for P-values <0.001, ** for P-values <0.01, * for P-values <0.05

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