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Table 1 Population characteristics at primary infection

From: Spatiotemporal dynamics of HIV-1 transmission in France (1999–2014) and impact of targeted prevention strategies

 

Not clustered individuals

All clustered individuals

Large clustered individuals (≥3 individuals)

p value§

N

71.5% (969)

28.5% (387)

17% (231)

 

Age (years)

Median (min–max)

36 (17–79)

32.5 (18–68)

32 (18–64)

p < 0.01

Sex

 Male

83.0% (804)

95.9% (371)

98.2% (227)

p < 0.01

 Female

16.6% (161)

3.9% (15)

1.3% (3)

 NA

0.4% (4)

0.2% (1)

0.5% (1)

Ethnicity

 White

83.7% (811)

91.5% (354)

93.1% (215)

p < 0.01

 Black

12.8% (124)

5.7% (22)

3% (7)

 Asian

1.5% (15)

1.3% (5)

1.3% (3)

 Others/NA

2.0% (19)

1.6% (6)

2.6% (6)

Origin

 Paris areaa

38.4% (372)

37% (143)

41.6% (96)

p = 0.66

 Other French regions

55.3% (536)

56.8% (220)

52.8% (122)

 Overseas

6.3% (61)

6.2% (24)

5.6% (13)

 

Risk

 MSM

65.6% (636)

85.8% (332)

88.3% (204)

p < 0.01

 HTS

27.6% (267)

7.5% (29)

4.3% (10)

 IDU

0.3% (3)

0% (0)

0% (0)

 Others/NA

6.5% (63)

6.7% (26)

7.4% (17)

Year of diagnosis

 1999–2005

38.4% (372)

24.8% (96)

20.3% (47)

p < 0.01

 2006–2010

34.2% (332)

40.6% (157)

43.7% (101)

 2011–2014

27.4% (265)

34.6% (134)

35.9% (83)

CD4 (cells/µL)—median (IQR)

506 (382–655)

522 (382–655)

525 (379–659)

p = 0.25

HIV-RNA level

Log10 copies/mL—median (IQR)

5.1 (4.4–5.8)

5.2 (4.7–5.8)

5.2 (4.6–5.8)

p = 0.15

HIV-1 subtype

 B

71.5% (693)

74.9% (290)

69.2% (160)

p = 0.01

 CRF02_AG

13.4% (130)

20.4% (79)

28.1% (65)

 A

3.2% (31)

0.2% (2)

0

 C

2.4% (23)

0% (0)

0

 Others

9.5% (92)

3.8% (16)

2.6% (6)

  1. MSM man who have sex with men, HTS heterosexual individual, IDU injection drug user
  2. §Statistical significance was assessed between clustering and non-clustering individuals
  3. aZipcodes: 75, 91, 92,93, 94 and 95;  Chi square test for trend