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Table 1 Population characteristics at primary infection

From: Spatiotemporal dynamics of HIV-1 transmission in France (1999–2014) and impact of targeted prevention strategies

  Not clustered individuals All clustered individuals Large clustered individuals (≥3 individuals) p value§
N 71.5% (969) 28.5% (387) 17% (231)  
Age (years)
Median (min–max)
36 (17–79) 32.5 (18–68) 32 (18–64) p < 0.01
Sex
 Male 83.0% (804) 95.9% (371) 98.2% (227) p < 0.01
 Female 16.6% (161) 3.9% (15) 1.3% (3)
 NA 0.4% (4) 0.2% (1) 0.5% (1)
Ethnicity
 White 83.7% (811) 91.5% (354) 93.1% (215) p < 0.01
 Black 12.8% (124) 5.7% (22) 3% (7)
 Asian 1.5% (15) 1.3% (5) 1.3% (3)
 Others/NA 2.0% (19) 1.6% (6) 2.6% (6)
Origin
 Paris areaa 38.4% (372) 37% (143) 41.6% (96) p = 0.66
 Other French regions 55.3% (536) 56.8% (220) 52.8% (122)
 Overseas 6.3% (61) 6.2% (24) 5.6% (13)  
Risk
 MSM 65.6% (636) 85.8% (332) 88.3% (204) p < 0.01
 HTS 27.6% (267) 7.5% (29) 4.3% (10)
 IDU 0.3% (3) 0% (0) 0% (0)
 Others/NA 6.5% (63) 6.7% (26) 7.4% (17)
Year of diagnosis
 1999–2005 38.4% (372) 24.8% (96) 20.3% (47) p < 0.01
 2006–2010 34.2% (332) 40.6% (157) 43.7% (101)
 2011–2014 27.4% (265) 34.6% (134) 35.9% (83)
CD4 (cells/µL)—median (IQR) 506 (382–655) 522 (382–655) 525 (379–659) p = 0.25
HIV-RNA level
Log10 copies/mL—median (IQR)
5.1 (4.4–5.8) 5.2 (4.7–5.8) 5.2 (4.6–5.8) p = 0.15
HIV-1 subtype
 B 71.5% (693) 74.9% (290) 69.2% (160) p = 0.01
 CRF02_AG 13.4% (130) 20.4% (79) 28.1% (65)
 A 3.2% (31) 0.2% (2) 0
 C 2.4% (23) 0% (0) 0
 Others 9.5% (92) 3.8% (16) 2.6% (6)
  1. MSM man who have sex with men, HTS heterosexual individual, IDU injection drug user
  2. §Statistical significance was assessed between clustering and non-clustering individuals
  3. aZipcodes: 75, 91, 92,93, 94 and 95;  Chi square test for trend