Fig. 3
Aggregate analysis of HIV envelope proteins from the 22 transmission pairs included in this study. GEE-derived p values indicate whether genotypic and phenotypic parameters are significantly different between infant and maternal groups, with p values ≤0.05 shown in red. The gray box indicates the 95% confidence interval and the whiskers indicate the 99% confidence interval. a Comparison of gp160 length (in number of amino acids) for all maternal and infant envelopes. b Comparison of gp160 glycosylation level (in number of PNG motifs) for maternal and infant envelopes. c–f Comparison of the mean 50% inhibitory concentration (IC50) of c PG9, d PG16, e TAK-779, and f sCD4 against envelopes from maternal and infant isolates. The number of envelope sequences tested for each group (n) is also shown