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Fig. 6 | Retrovirology

Fig. 6

From: Identification of small molecule modulators of HIV-1 Tat and Rev protein accumulation

Fig. 6

791, 833, and 892 inhibit cytoplasmic accumulation of HIV-1 US RNA. HeLa rtTA HIV GagGFP C7 cells were treated with 791 (30 µM), 833 (2 µM), or 892 (15 µM) for 4 h prior to Dox induction. Cells were fixed 24 h after Dox addition and processed for FISH using probes to HIV-1 US RNA. Representative fluorescent in situ hybridization images of cells treated with DMSO or the indicated compounds (N ≥ 3). Cells were viewed at 630X (oil immersion) magnification. Images are cropped to show a representative field of view

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