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Fig. 1 | Retrovirology

Fig. 1

From: HIV signaling through CD4 and CCR5 activates Rho family GTPases that are required for optimal infection of primary CD4+ T cells

Fig. 1

Effect of small molecule inhibitors on viral fusion. Viral fusion was quantified using β-lactamase mediated cleavage of CCF2-AM fluorescent substrate. Primary CD4+ T cells were infected with CXCR4-tropic viruses following treatment to small molecule inhibition. Results are graphed as fold change to untreated control on log2 axis. Experimental conditions were performed in triplicate. Error bars represent SEM

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