HIV integration sites in latently infected cell lines: evidence of ongoing replication

Retrovirology

Table 1 Cell lines analysed in this study from NIH AIDS reagent program

Cell line	Replication competent virus	Site of mutation	Proviral copies reported per cell	Reference
U1	Yes	Mutation in tat	2	[6]
ACH-2	Yes	Mutation in tar	1	[7, 8]
J1.1	Yes	Wild type	1	[9]
J-Lat 8.4	No	Frame shift env	1	[10]
J-Lat 9.2	No	Frame shift env	1	[10]
J-Lat 10.6	No	Frame shift env	1	[10]
J-Lat 15.4	No	Frame shift env	1	[10]
J-Lat tat-GFP 8.2	No	LTR-tat-GFP	1	[10, 11]
J-Lat tat-GFP A1	No	LTR-tat-GFP	1	[10, 11]
J-Lat tat-GFP H2	No	LTR-tat-GFP	1	[10, 11]
J-Lat tat-GFP A72	No	LTR-tat-GFP	1	[10, 11]

ENV envelope, LTR long terminal repeat, tat trans-activator of transcription, GFP green fluorescent protein

ISSN: 1742-4690