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Fig. 2 | Retrovirology

Fig. 2

From: Ultrasensitive single-genome sequencing: accurate, targeted, next generation sequencing of HIV-1 RNA

Fig. 2

Neighbor joining trees comparing PCR recombination in each method. Neighbor joining trees rooted on NL4-3 generated from randomly selected sets of 50 supermajority sequences obtained from mixtures of WT and Mutant BH10 pol transcripts. Reference sequences for the BH10 mutant and WT and NL4-3 WT are shown in large blue, black and green squares, respectively. Sequences matching the references are shown in the same colors as the references. The orange circles show an intermediate step in the bioinformatics computations and represent those sequences identified as PCR recombinant species that would be lost from the respective data sets after they were deleted in the final steps of the pipeline

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