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Fig. 6 | Retrovirology

Fig. 6

From: First Phase I human clinical trial of a killed whole-HIV-1 vaccine: demonstration of its safety and enhancement of anti-HIV antibody responses

Fig. 6

Neutralizing antibody response after vaccination. The analysis of the neutralizing antibodies before (green bar) and 4 weeks after (red bar) vaccination were carried out with 1:30 dilutions of sera and luciferase reporter gene expression was determined with Britelite (Perkin Elmer) using a Victor V plate reader (Perkin Elmer) (a). Neutralization activity of serial dilutions of high neutralizing antibodies of participants’ sera (red numbers on Fig. 5a) at both pre- and post-vaccination, using PRB926-04.A9.4237 (subtype B) and Q168ENVa2 (subtype A). Each data point represents the average IC50 of a single serum sample tested with the either virus, and the data from pre- and post-vaccination samples were paired for comparison (b). NA not available

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Retrovirology

ISSN: 1742-4690

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