Fig. 4

Nonspecific ADCC activities mediated by CD56+ T cells and CD56+ NK cells in long-term HIV-1-monoinfected FPDs, HIV-1/HCV-coinfected FPDs, and healthy donors. a Representative flow plots showed the levels of CD107a expression and IFNγ production from CD56+ T cells and CD56+ NK cells in HIV-1 infected subjects and healthy controls. b Comparison of percentages of CD107a+ (left panel) or IFNγ+ (right panel) cells in CD56+ T cells and CD56+ NK cells between HIV-1 infected subjects and healthy controls. c The frequencies of CD56+ T cells and CD56+ NK cells in peripheral lymphocytes in HIV-1 infected subjects and healthy controls. d The percentages of CD16+ cells in CD56+ T cells and CD56+ NK cells of HIV-1 infected subjects and healthy controls. e Correlations between the MFI loss of CD16 and expression of CD107a in CD56+ T cell-mediated nonspecific ADCC in HIV-1/HCV-coinfected (dash line) and HIV-1-monoinfected groups (solid line). f Correlations between CD107a expression and IFNγ production in CD56+ T cell-mediated nonspecific ADCC in HIV-1/HCV-coinfected (dash line) and HIV-1-monoinfected groups (solid line). The horizontal bar indicated median values. All P values were two-tailed and considered significant when lower than 0.05