Fig. 7From: Membrane bound modified form of clade B Env, JRCSF is suitable for immunogen design as it is efficiently cleaved and displays all the broadly neutralizing epitopes including V2 and C2 domain-dependent conformational epitopesN197D mutant of JRCSF retains native conformation. FACS-based cell surface staining assay of JRFL, JRCSF and JRCSF (N197D) with glycan and quaternary epitope-dependent bNAbs PG9 and PGT128 and CD4i Abs 17b and 412d over a range of antibody concentrationsBack to article page