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Fig. 1 | Retrovirology

Fig. 1

From: Membrane bound modified form of clade B Env, JRCSF is suitable for immunogen design as it is efficiently cleaved and displays all the broadly neutralizing epitopes including V2 and C2 domain-dependent conformational epitopes

Fig. 1

Differential binding of JRFL and JRCSF to CD4-bs-directed bNAbs b12 and VRC01. FACS-based cell surface staining assay was used to measure binding of a glycan-dependent antibody 2G12, b, c CD4-bs-directed bNAbs b12 and VRC01, and d, e CD4-bs-directed non-NAbs F105 and b6 to JRFL and JRCSF over a range of antibody concentration

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Retrovirology

ISSN: 1742-4690

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