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Table 2 Maximal percent inhibition (MPI) of selected HIV-1 subtype C Envs by maraviroc in 293-Affinofile CD4med/CCR5hi cells

From: Frequency and Env determinants of HIV-1 subtype C strains from antiretroviral therapy-naive subjects that display incomplete inhibition by maraviroc

Patient ID

Env clone

MPI (%)a

SD (%)b

204

E-15

100.13

1.66

E-7

68.65

16.62

550

I-32

92.7

0.62

I-2

49.03

13.75

I-7

65.38

3.33

F-12

43.39

1.42

F-20

62.65

2.09

1375

E-21

100.01

0.69

E-2

16.54

10.53

I-8

30.87

9.17

1441

E-7

99.25

0.56

E-1

60.47

3.94

E-2

48.02

5.56

E-6

36.85

12.35

I-2

32.92

12.34

I-9

27.51

0.05

1684

I-13

100.27

1.46

E-7

72.63

2.91

2042

E-26

100.99

1.57

I-38

63.55

1.30

  1. MPI maximal percent inhibition, SD standard deviation
  2. aMean and b standard deviation of three independent experiments
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Retrovirology

ISSN: 1742-4690

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