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Table 1 Absence of BLV DNA in 51 whole genomes of breast tumors

From: Whole genome sequencing of 51 breast cancers reveals that tumors are devoid of bovine leukemia virus DNA

Subject ID Country Age Diagnosis Sample type Grade HER2 status ER status PR status Total no of reads No. of reads that align on
Control DNA (nuclear) Control DNA (mitochondrial) BLV_AF033818 BLV_AF257515 BLV_D00647 BLV_K02021 BLV_LC080667
MEX-BR-106 Mexico 42 IDC Tumor II + + 583,906,975 669 396,239 0 0 0 0 0
MEX-BR-116 Mexico 92 IDC Tumor III + 577,618,196 796 1,166,916 0 0 0 0 0
MEX-BR-15 Mexico 45 IDC Tumor II + + 571,043,227 652 1,167,672 0 0 0 0 0
MEX-BR-154 Mexico 52 IDC Tumor III + + 700,630,351 811 400,383 0 0 0 0 0
MEX-BR-165 Mexico 42 IDC Tumor II + + 757,323,566 737 742,646 0 0 0 0 0
MEX-BR-198 Mexico 44 IDC Tumor II + + 745,509,529 1019 1,264,555 0 0 0 0 0
MEX-BR-50 Mexico 47 IDC Tumor II + + 605,198,587 653 958,812 0 0 0 0 0
MEX-BR-82 Mexico 59 IDC Tumor II + 681,881,066 687 547,863 0 0 0 0 0
BRC12 USA 81 IDC Tumor II U U 548,255,169 745 1,113,306 0 0 0 0 0
BRC13 USA 51 IDC Tumor III 7 U 587,461,482 686 1,106,780 0 0 0 0 0
BRC14 USA 86 IDC Tumor III 7 U 755,094,207 899 1,469,976 0 0 0 0 0
BRC15 USA 83 IDC Tumor II 7 U 758,784,262 934 2,327,824 0 0 0 0 0
BRC16 USA 61 IDC Tumor III 7 U 821,134,040 1287 2,084,782 0 0 0 0 0
BRC18 USA 85 IDC Tumor I 8 U 568,355,455 677 1,395,823 0 0 0 0 0
BRC19 USA 75 IDC Tumor II 8 U 596,337,842 747 1,648,870 0 0 0 0 0
BRC20 USA 61 IDC Tumor III 4 U 507,651,900 570 1,026,830 0 0 0 0 0
BRC21 USA 73 IDC Tumor I 7 U 719,742,122 817 1,710,010 0 0 0 0 0
BRC22 USA 64 ILC Tumor I 6 U 608,469,920 708 953,100 0 0 0 0 0
BRC23 USA 68 IDC Tumor I 7 U 613,481,215 687 1,272,519 0 0 0 0 0
BRC24 USA 51 IDC Tumor II 7 U 656,115,800 721 1,980,030 0 0 0 0 0
BRC25 USA 52 IDC Tumor II 5 U 583,560,227 712 580,203 0 0 0 0 0
BRC28 USA 52 IDC Tumor I 7 U 664,667,777 781 973,990 0 0 0 0 0
BRC29 USA 74 IDC Tumor III 6 U 785,019,563 596 2,085,482 0 0 0 0 0
BRC3 USA 62 IDC Tumor II 8 U 695,174,967 1026 3,134,341 0 0 0 0 0
BRC30 USA 60 ILC Tumor II 5 U 663,769,744 794 1,442,014 0 0 0 0 0
BRC31 USA 66 IDC Tumor II 6 U 734,384,352 1028 1,415,996 0 0 0 0 0
BRC32 USA 54 IDC Tumor I 7 U 643,884,178 703 1,404,436 0 0 0 0 0
BRC33 USA 83 IDC Tumor II 8 U 660,668,877 819 1,284,599 0 0 0 0 0
BRC34 USA 79 IDC Tumor I 7 U 572,861,930 704 1,499,414 0 0 0 0 0
BRC35 USA 76 IDC Tumor II 6 U 543,480,474 697 1,709,943 0 0 0 0 0
BRC36 USA 68 IDC Tumor II 7 U 706,448,348 804 1,501,763 0 0 0 0 0
BRC40 USA 66 IDC Tumor I 8 U 600,847,516 690 1,686,112 0 0 0 0 0
BRC41 USA 55 IDC Tumor II 8 U 689,312,217 812 3,735,591 0 0 0 0 0
BRC42 USA 74 IDC Tumor II U U 684,312,302 685 1,308,948 0 0 0 0 0
BRC44 USA 64 IDC Tumor II 7 U 717,390,251 891 1,430,064 0 0 0 0 0
BRC47 USA 54 IDC Tumor III 5 U 580,674,755 865 960,944 0 0 0 0 0
BRC48 USA 66 IDC Tumor II 6 U 782,262,353 783 1,236,102 0 0 0 0 0
BRC49 USA 56 IDC Tumor II 8 U 577,656,003 559 881,804 0 0 0 0 0
BRC5 USA 72 IDC Tumor II 7 U 762,026,860 1155 2,462,819 0 0 0 0 0
BRC50 USA 78 ILC Tumor I 4 U 661,525,693 792 357,915 0 0 0 0 0
BRC7 USA 78 IDC Tumor II 8 U 455,727,994 795 580,484 0 0 0 0 0
BRC8 USA 87 IDC Tumor I 8 U 518,548,285 628 1,394,439 0 0 0 0 0
BRC9 USA 65 ILC Tumor II 8 U 516,702,802 697 1,759,444 0 0 0 0 0
9DDA1 Vietnam 60 IDC Tumor III U U U 706,450,950 759 1,109,340 0 0 0 0 0
9P4X9 Vietnam 54 IDC Tumor III U U U 610,913,537 778 619,066 0 0 0 0 0
9YBUF Vietnam 52 IDC Tumor III U U U 595,959,881 616 788,058 0 0 0 0 0
CI5PD Vietnam 51 IDC Tumor III U U U 572,612,309 626 786,787 0 0 0 0 0
FYGW6 Vietnam 38 IDC Tumor III U U U 238,201,059 282 221,942 0 0 0 0 0
GT33 V Vietnam 52 IDC Tumor III U U U 548,640,325 604 766,320 0 0 0 0 0
SX1A2 Vietnam 53 IDC Tumor III U + + 598,405,143 693 1,002,577 0 0 0 0 0
UQWDS Vietnam 35 IDC Tumor III U 596,126,825 665 1,285,884 0 0 0 0 0
9DDA1 Vietnam 60 IDC Normal III U U U 691,060,649 797 1,122,133 0 0 0 0 0
9P4X9 Vietnam 54 IDC Normal III U U U 601,815,791 664 694,153 0 0 0 0 0
9YBUF Vietnam 52 IDC Normal III U U U 593,968,922 646 1,202,175 0 0 0 0 0
CI5PD Vietnam 51 IDC Normal III U U U 566,065,567 595 911,133 0 0 0 0 0
FYGW6 Vietnam 38 IDC Normal III U U U 337,274,647 386 361,063 0 0 0 0 0
GT33 V Vietnam 52 IDC Normal III U U U 581,403,783 652 1,189,003 0 0 0 0 0
SX1A2 Vietnam 53 IDC Normal III U + + 608,739,604 700 878,362 0 0 0 0 0
UQWDS Vietnam 35 IDC Normal III U 590,387,671 685 829,847 0 0 0 0 0
MEX-BR-106 Mexico 42 IDC Normal II + + 539,137,287 526 351,034 0 0 0 0 0
MEX-BR-116 Mexico 92 IDC Normal III + 513,833,151 520 258,287 0 0 0 0 0
MEX-BR-123 Mexico 71 IDC Normal III + U 668,026,494 761 515,501 0 0 0 0 0
MEX-BR-15 Mexico 45 IDC Normal II + + 592,958,041 670 756,778 0 0 0 0 0
MEX-BR-154 Mexico 52 IDC Normal III + + 670,289,201 929 817,446 0 0 0 0 0
MEX-BR-165 Mexico 42 IDC Normal II + + 712,308,425 706 537,516 0 0 0 0 0
MEX-BR-198 Mexico 44 IDC Normal II + + 726,225,752 831 216,109 0 0 0 0 0
MEX-BR-200 Mexico 42 IDC Normal II + + 767,097,542 1197 279,031 0 0 0 0 0
MEX-BR-28 Mexico 79 MC Normal II + + 588,561,634 607 215,022 0 0 0 0 0
MEX-BR-50 Mexico 47 IDC Normal II + + 551,537,695 618 394,842 0 0 0 0 0
MEX-BR-82 Mexico 59 IDC Normal II + 608,849,308 719 385,789 0 0 0 0 0
  1. Whole genome sequencing data from 51 breast tumors and 19 normal adjacent breast tissues were downloaded from the NCBI dbGaP. Hundreds of millions of paired-reads per sample were probed for alignment on different BLV strains and on nuclear and mitochondrial human control sequences
  2. IDC infiltrating ductal carcinoma, ILC infiltrating lobular carcinoma, MC mixed carcinoma, U unknown