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Fig. 2 | Retrovirology

Fig. 2

From: Type I interferon responses are impaired in latently HIV infected cells

Fig. 2

IFNα-induced expression of MHC-I is impaired in latently HIV-infected U1 and OM10.1 cells. Cell lines were stimulated with 10, 100, or 1000 U/mL of exogenous IFNα for 24 h. Following stimulation, cells were collected and surface expression of MHC-I was assessed by flow cytometry. Representative histogram and summary data of IFNα-induced MHC-I expression normalized to unstimulated controls is shown for a U937 and U1 cells (n = 6) and b HL60 and OM10.1 cells (n = 6). p < 0.0001 by one-way ANOVA and p < 0.05 by pairwise Dunnett’s test compared to unstimulated cells. *p < 0.05; **p < 0.01, and ***p < 0.001 by Two-way ANOVA with Bonferroni post-test for multiple comparisons

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