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Fig. 3 | Retrovirology

Fig. 3

From: The HIV-1 late domain-2 S40A polymorphism in antiretroviral (or ART)-exposed individuals influences protease inhibitor susceptibility

Fig. 3

Mutation of S40 to Ala minimally affects virus budding, maturation, or infectivity. a–c Electron microscopy of particles associated with cells transfected with pEnv and pNL4-3ΔEnv-WT (a), -S40A (b), or -S40F (c). Particle exhibiting mature morphology were quantified compared to WT (f). d p24 capsid antigen detected in culture media, as indicated by triplicate ELISA; e Viral particle infectivity, determined by MAGI assay, done in triplicate

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Retrovirology

ISSN: 1742-4690

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