Fig. 6

Impact of sequence divergence in V3 on the tolerance to the polymorphism at position 202. a Left, schematic drawing of B 202G-V3C and B V3C Env (wt Env used to construct these Env are given as reference for the color code, at the top). Right, functionality of B 202G-V3C and B V3C. b Sequence alignment of V3 of the Env B and G (top) and C and G (bottom) with annotated the 10 and 5 diverging residues, respectively (numbering is according to HxB2). Color code is the same as for Fig. 2a