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Fig. 4 | Retrovirology

Fig. 4

From: Lack of concordance between residual viremia and viral variants driving de novo infection of CD4+ T cells on ART

Fig. 4

Viral diversity during active replication. Maximum likelihood phylogenetic trees (unrooted) of viral variants detected at virologic failure (just before treatment switch): a Patient 1; b Patient 2; c Patient 3. Plasma viremia sequences (gold) and episomal vDNA from PBMCS (violet) are highlighted; proviral DNA from the CD4+ T-cells (grey) is also included. Major plasma/episomal clusters are highlighted when clearly distinguished (Pt-1 and Pt-3), and the frequency of sequences included is color-coded at each tree (in percentages). In B (Pt-2), the overall result from the Env-tropism prediction is indicated

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Retrovirology

ISSN: 1742-4690

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