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Fig. 2 | Retrovirology

Fig. 2

From: HIV-1 escapes from N332-directed antibody neutralization in an elite neutralizer by envelope glycoprotein elongation and introduction of unusual disulfide bonds

Fig. 2

Sensitivity of viral isolates from individual D16916 to bNAbs. Clonal HIV-1 variants from 7 and 11 months post-SC were tested for their neutralization sensitivity against bNAbs PGT135 (a), b12 (b), 12A21 (c), PG16 (d) and PGT145 (e) and grouped according to their target epitope OD-glycan, CD4-bs and V1V2 apex. The graphs show IC50 values for each virus isolate, as determined by linear regression. Differences were considered statistically significant when p values were ≤ 0.05, represented by asterisks (*p ≤ 0.05; **p ≤ 0.005, ***p ≤ 0.001). The horizontal bars represent the median IC50 value per time point

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