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Table 2 Founder and escape lineages of a given epitope from each subject’s single time point sequence data

From: Molecular clock of HIV-1 envelope genes under early immune selection

Patient Number of envelope sequences Escape details
CH077   gp160 (352–361)
 Founder-lineage 9 QFRNKTIVF
 Escape-mutant 1 38 QFKNKTIVF
 Escape-mutant 2 4 QFRNKAIVF
CH164   gp160 (2–10)
 Founder-lineage 5 RVMETRRSW
 Escape-mutant 1 10 RVMKTRRSW
 Escape-mutant 2 8 RVMGTRRSW
SUMA0874   gp160 (744–753)
 Founder-lineage 18 RSSRLVDGFL
 Escape-mutant 1 6 RSGRLVDGFL
 Escape-mutant 2 4 RSSCLVDGFL
WEAU0575   gp160 (31–39)
 Founder-lineage 24 AENLWVTVY
 Escape-mutant 1 18 AEKLWVTVY
 Escape-mutant 2 7 TENLWVTVY
 Escape-mutant 3 5 VENLWVTVY
 Escape-mutant 4 4 AKNLWVTVY
  1. The sequence data from subject CH077, SUMA0874, and WEAU0575 are obtained from Ref. [30] and the sequence data from subject CH164 are obtained from Ref. [32]. The sample time point is 14, 56, 30, and 15 days after the first sample at Fiebig stage I/II for subject CH077, CH164, SUMA, and WEAU, respectively