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Fig. 2 | Retrovirology

Fig. 2

From: Molecular clock of HIV-1 envelope genes under early immune selection

Fig. 2

Individual HIV-1 diversity dynamics. Each of the 15 subjects’ diversity dynamics as a function of time over 2 years since the first sample. The dotted line of each panel indicates the neutral diversification rate, \(2.16 \times 10^{ - 5}\) per site per day [3335], and the solid curve denotes the best-fit of the mixed effects model. All 15 subjects show a statistically significant linear increase in diversity over time; subjects CH077, CH131, CH159 and CH505’s quadratic increases are statistically significant. The linear diversification rate for the first 150 days of each individual is listed in Table 1 and the linear and quadratic diversification rates over 2 years are listed in Additional file 1: Table S1

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