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Table 1 Identification of HIV-1 Tat and LTR sequences co-linear to CCR5- and CXCR4-utilizing Env-V3 sequences defined by Web-PSSM scoring

From: Utilization of HIV-1 envelope V3 to identify X4- and R5-specific Tat and LTR sequence signatures

Genomic region CCR5 CXCR4
gp120 1678 52
Tat 504 31
LTR 615 35
  1. HIV-1 amino acid sequences for gp120 and Tat and nucleotide sequences for LTR were classified as being derived from CCR5- or CXCR4-utilizing genomes according to Web-PSSM prediction scores utilizing the Env-V3 sequence. Sequences with intermediate scores PSSM scores are derived from R5, X4, or dual-tropic X4/R5 viruses and were not included in further analysis