Fig. 2

Viral replication kinetics over a 7-day period in PM1 cells. PM1 cells were infected with the same amount of p24 for all viral stocks. Levels of p24 production in cell-free supernatants were monitored at days 3 and 7 p.i. WT, R263K and H51Y/R263K viruses are also presented in each data series from a to f. a K65R series, b L74V series, c K103N series, d E138K series, e M184I series, and f M184V series. Values were calculated from three independent infections. Error bars indicate mean ± SD. ND not detectable