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Table 7 Longitudinal analysis of Tat-mediated Env entry in DC versus CD4+ T-cell counts

From: HIV-Tat immunization induces cross-clade neutralizing antibodies and CD4+ T cell increases in antiretroviral-treated South African volunteers: a randomized phase II clinical trial

Treatment

Estimate

95 % CI

p value

Vaccinees

−127

−208

−45

0.0023

Placebo

−72

−194

51

0.2515

  1. A significant inverse relationship was observed between CD4+ T cells and the Tat-mediated Env entry in DC in the presence of sera from vaccinees (n = 19) but not from placebo (n = 11) indicating a positive relationship of CD4+ T-cell increases with neutralization of Env entry in DC. A longitudinal analysis for repeated measures by generalized estimating equation method was used for the analysis
  2. CI confidence interval
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Retrovirology

ISSN: 1742-4690

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