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Table 1 Baseline characteristics of study participants

From: HIV-Tat immunization induces cross-clade neutralizing antibodies and CD4+ T cell increases in antiretroviral-treated South African volunteers: a randomized phase II clinical trial

 

n

Vaccinees

n

Placebo

Gender

 Male

32

32.0 %

20

20.0 %

 Female

68

68.0 %

80

80.0 %

Race

 Black

100

100.0 %

99

99.0 %

 Caucasian

0

0.0 %

0

0.0 %

 Mixed

0

0.0 %

1

1.0 %

Age

 Mean ± SD

100

36.1 ± 5.6

100

36.0 ± 6.2

 Range

 

21.1–45.8

 

19.6–45.4

CD4+ (cells/μL)

 Mean ± SD

99

510 ± 229

100

563 ± 195

 Range

 

137–1530

 

242–1252

CD4+ (%)

 Mean ± SD

99

28 ± 8

100

29 ± 7

 Range

 

7–49

 

17–42

HIV RNA (copies/mL)

 <40 (assay cut-off)

94

95.0 %

96

96.0 %

 ≥40

5

5.0 %

4

4.0 %

Years from HIV diagnosis

 Mean ± SD

100

5.0 ± 3.0

100

4.9 ± 3.3

 Range

 

1.0–14.0

 

1.0–19.0

Years from cART initiation

 Mean ± SD

100

3.5 ± 2.0

100

3.3 ± 2.1

 Range

 

0.7–8.2

 

0.6–8.9

cART regimen

 NNRTI or NRTI-based

97

97.0 %

98

98.0 %

 PI-based

3

3.0 %

2

2.0 %

Previous tuberculosis

29

29.0 %

34

34.0 %

  1. n number of individuals, SD standard deviation