Fig. 6

Inhibition of Tat altered miRNAs recapitulates the observed suppression of β-catenin activity in U-87MG and HeLa cells. a U-87MG and b HeLa cells were transfected with a β-catenin responsive luciferase vector and antagomirs that inhibit the indicated miRNAs. Twenty-four hours later cells were treated with LiCl to induce activation of β-catenin. Twenty-four hours post LiCl treatment luciferase was measured and displayed as a percentage of maximal activity. *p ≤ 0.05; **p ≤ 0.01; ***p ≤ 0.001