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Fig. 3 | Retrovirology

Fig. 3

From: The interferon-induced antiviral protein PML (TRIM19) promotes the restriction and transcriptional silencing of lentiviruses in a context-specific, isoform-specific fashion

Fig. 3

mPML knockout increases HIV-1 LTR-driven GFP expression. PML-KO and WT MEFs were infected with increasing doses of HIV-1NL-GFP and cells were maintained in culture for 2 days (a) or 10 days (b), followed by FACS analysis. The percentage of infected (GFP-expressing) cells and the mean fluorescence intensity (MFI) were measured at each time point (top and bottom panels, respectively) (**P < 0.01; ***P < 0.001; one-tailed paired Student’s t test)

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