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Fig. 7 | Retrovirology

Fig. 7

From: Spatiotemporal hierarchy in antibody recognition against transmitted HIV-1 envelope glycoprotein during natural infection

Fig. 7

Determination of major antigenic subdomains for autologous neutralization by comparing neutralizing sensitivity of parental and subdomain-specific chimeras to sequential plasma samples from P08 and P11. a Percent neutralization on the y axis indicates the reduction in luciferase activity in the presence of plasma verse those without. b Half-maximal inhibitory dilutions (ID50) were calculated as the dilution at which the plasma demonstrated inhibition of 50 % infection compared with the controls. The actual Ka values for corresponding plasma samples against each subdomain were also included for comparative purpose. Different color intensities correspond to different ID50 and Ka values for clarity, lighter for lower and darker for higher. ND not detectable

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