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Fig. 1 | Retrovirology

Fig. 1

From: Human endogenous retrovirus (HERV) expression is not induced by treatment with the histone deacetylase (HDAC) inhibitors in cellular models of HIV-1 latency

Fig. 1

The HDAC inhibitors promote histone acetylation and HIV-1 p24 expression. a Treatment of U1 cells with HDAC inhibitors results in increased acetylation of histone H4. The blot was probed with antibody to acetylated H4, followed by HRP-conjugated secondary antibody and enhanced chemiluminescence (ECL) detection. Subsequently, the same blots were reprobed with anti-β-actin antibody. The lanes are (1) untreated, (2) vorinostat, (3) panobinostat, (4) romidepsin, (5) prostratin and (6) PMA. b HIV-1 p24 expression is induced by vorinostat, panobinostat, romidepsin, prostratin and PMA, as measured by flow cytometry

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Retrovirology

ISSN: 1742-4690

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