Fig. 6From: Mechanisms of escape from the PGT128 family of anti-HIV broadly neutralizing antibodiesImportance of V3 loop residues for promiscuous binding of the mannose-patch. V3 loop residues in the a, b 7AA N295 N332 and c, d 7AA N295 N334 variants were mutated to WT and the impact on neutralization measured for PGT128 and PGT130. Mutations in the V3 loop were made to e, f IAVI C22 N334 and g, h 6545.v4.c1 to confer neutralization sensitivity by PGT128 and PGT130Back to article page