From: Genetic Evolution during the development of an attenuated EIAV vaccine
 | Virulenta | Avirulentb | p | Vivoc | Vitrod | p e | |
---|---|---|---|---|---|---|---|
Gag | 100A/T | 19 (31) | 25 (36) | <0.01 | 0 (8) | 45 (49) | <0.01 |
103T/S | 14 (31) | 24 (26) | <0.01 | 0 (8) | 41 (49) | <0.01 | |
447N/D | 12 (31) | 16 (26) | >0.05 | 0 (8) | 28 (49) | <0.01 | |
484D/N | 0 (31) | 17 (26) | <0.01 | 0 (8) | 19 (49) | >0.05 | |
Pol | 16K/E | 16 (28) | 26 (26) | <0.01 | 0 (8) | 19 (47) | >0.05 |
27E/G | 10 (28) | 17 (26) | 0.05 < p < 0.01 | 0 (7) | 42 (47) | <0.01 | |
64G/E | 0 (28) | 20 (26) | <0.01 | 0 (7) | 27 (47) | 0.05 < p < 0.01 | |
598K/R | 6 (28) | 26 (26) | <0.01 | 0 (7) | 20 (47) | >0.05 | |
619N/D | 1 (28) | 15 (26) | <0.01 | 0 (7) | 23 (47) | 0.05 < p < 0.01 | |
820I/M | 0 (28) | 17 (26) | <0.01 | 0 (7) | 16 (47) | >0.05 | |
gp90 | 46A/E | 28 (65) | 48 (48) | <0.01 | 0 (35) | 76 (78) | <0.01 |
98G/R | 29 (65) | 45 (48) | <0.01 | 0 (35) | 75 (78) | <0.01 | |
100K/(H)Q | 46 (65) | 48 (48) | <0.01 | 16 (35) | 78 (78) | <0.01 | |
103H/Y | 30 (65) | 45 (48) | <0.01 | 0 (35) | 75 (78) | <0.01 | |
180E/K | 1 (65) | 22 (48) | <0.01 | 1 (35) | 22 (78) | <0.01 | |
189K/E | 27 (65) | 46 (48) | <0.01 | 0 (35) | 73 (78) | <0.01 | |
190E/K | 27 (65) | 48 (48) | <0.01 | 0 (35) | 74 (78) | <0.01 | |
193S/N | 31 (65) | 48 (48) | <0.01 | 1 (35) | 78 (78) | <0.01 | |
236D/-(N) | 9 (65) | 45 (48) | <0.01 | 0 (35) | 54 (78) | <0.01 | |
237N/K | 0 (65) | 36 (48) | <0.01 | 0 (35) | 67 (78) | <0.01 | |
246N/K | 5 (65) | 29 (48) | <0.01 | 0 (35) | 33 (78) | <0.01 | |
247E/K | 4 (65) | 24 (48) | <0.01 | 0 (35) | 28 (78) | <0.01 | |
321K/E(N) | 31 (65) | 48 (48) | <0.01 | 1 (35) | 78 (78) | <0.01 | |
410H/Q | 19 (65) | 37 (48) | <0.01 | 0 (35) | 56 (78) | <0.01 | |
gp45 | 58V(I)/T | 5 (32) | 15 (23) | <0.01 | 0 (10) | 26 (45) | >0.05 |
Tat | 7R/H | 14 (34) | 29 (29) | <0.01 | 0 (10) | 43 (53) | <0.01 |
S2 | 41T/I | 16 (34) | 28 (30) | <0.01 | 0 (10) | 44 (54) | <0.01 |
51T/I | 15 (34) | 28 (30) | <0.01 | 0 (10) | 41 (54) | <0.01 | |
55Q/K | 18 (34) | 30 (30) | <0.01 | 0 (10) | 46 (54) | <0.01 | |
Rev | 74V/I | 2 (35) | 19 (27) | <0.01 | 0 (10) | 21 (52) | <0.01 |
LTR | AP-1 | 4 (77) | 57 (65) | <0.01 | 0 (38) | 61 (104) | <0.01 |
MDBP | 14 (77) | 33 (65) | <0.01 | 1 (38) | 46 (104) | <0.01 | |
E_box | 30 (77) | 56 (65) | <0.01 | 0 (38) | 86 (104) | <0.01 |