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Table 1 Comparison of nucleotide and amino acid genetic distances of the various EIAVs compared to EIAVLN40 and EIAVDV117

From: Genetic Evolution during the development of an attenuated EIAV vaccine

  EIAVLN40 EIAVDV117
EIAVDV117 EIAVDLV34 EIAVDLV62 EIAVDLV92 EIAVDLV121 EIAVFDDV13 EIAVDLV34 EIAVDLV62 EIAVDLV92 EIAVDLV121 EIAVFDDV13
LTR nu 2.90 (0.85)a 3.30 (0.84) 4.18 (1.11) 4.18 (1.16) 4.06 (1.01) 5.86 (1.40) 1.94 (0.58) 2.97 (0.90) 3.68 (1.01) 2.59 (0.77) 3.71 (1.09)
Gag nu 2.02 (0.35) 1.72 (0.26) 1.96 (0.29) 2.16 (0.31) 2.30 (0.32) 2.47 (0.37) 2.13 (0.29) 2.31 (0.31) 2.58 (0.34) 2.62 (0.32) 2.57 (0.36)
aa 1.91 (0.51) 1.69 (0.42) 2.09 (0.53) 2.08 (0.53) 2.73 ± (0.58) 2.31 (0.57) 1.98 (0.45) 2.12 (0.50) 2.25 (0.53) 2.73 (0.54) 2.14 (0.50)
Pol nu 1.99 (0.24) 1.93 (0.16) 2.00 (0.10) 2.06 (0.19) 2.40 (0.20) 2.75 (0.23) 1.65 (0.16) 1.77 (0.16) 1.74 (0.17) 2.13 (0.19) 2.38 (0.23)
aa 2.03 (0.41) 2.13 (0.34) 2.27 (0.34) 2.38 (0.36) 2.49 (0.38) 2.84 (0.43) 1.35 (0.23) 1.69 (0.26) 1.61 (0.26) 1.79 (0.27) 2.00 (0.32)
gp90 nu 3.13 (0.43) 3.28 (0.39) 3.40 (0.41) 3.51 (0.41) 3.94 (0.44) 4.01 (0.48) 3.43 (0.40) 3.46 (0.42) 3.60 (0.43) 3.99 (0.43) 3.78 (0.46)
aa 4.20 (0.91) 5.17 (0.82) 5.17 (0.87) 5.55 (0.91) 6.07 (0.90) 6.71 (1.11) 6.38 (0.93) 6.20 (0.94) 6.38 (0.97) 7.05 (1.04) 7.59 (1.18)
gp45 nu 2.45 (0.38) 2.28 (0.29) 2.36 (0.26) 2.40 (0.29) 2.60 (0.31) 2.86 (0.41) 1.64 (0.23) 1.89 (0.23) 1.86 (0.27) 2.18 (0.29) 2.32 (0.40)
aa 3.31 (0.69) 3.14 (0.55) 3.56 (0.50) 3.22 (0.53) 3.42 (0.53) b 1.78 (0.41) 2.60 (0.44) 2.14 (0.47) 2.71 (0.53)
Tat nu 1.62 (0.73) 1.13 (0.36) 1.40 (0.45) 1.74 (0.57) 2.04 (0.67) 2.27 (0.79) 2.28 (0.72) 2.44 (0.75) 2.59 (0.78) 2.61 (0.80) 2.85 (0.90)
aa 2.05 (1.26) 2.26 (0.97) 2.93 (1.27) 3.76 (1.51) 4.38 (1.91) 5.11 (2.11) 2.98 (1.36) 3.29 (1.45) 3.81 (1.53) 3.19 (1.61) 3.93 (1.83)
S2 nu 1.97 (0.91) 1.72 (0.48) 2.14 (0.77) 2.45 (0.88) 2.94 (1.01) 2.45 (0.98) 3.00 (0.96) 3.31 (1.11) 3.12 (1.07) 4.10 (1.29) 2.85 (1.10)
aa 3.60 (2.20) 6.85 (2.51) 8.08 (3.23) 7.57 (2.99) 10.61 (3.81) 6.38 (3.10) 4.17 (1.36) 5.62 (2.47) 6.78 (2.75) 7.97 (3.09) 6.38 (3.13)
Rev nu 1.62 (0.50) 1.61 (0.37) 1.81 (0.33) 1.50 (0.34) 1.81 (0.35) 2.23 (0.65) 1.57 (0.39) 1.94 (0.39) 1.59 (0.39) 1.86 (0.38) 1.58 (0.54)
aa 2.52 (0.77) 3.29 (0.72) 2.48 (0.63) 3.64 (0.84) 5.70 (1.87) 3.47 (0.12) 4.25 (0.11) 3.66 (0.11) 4.45 (0.10) 4.77 (0.63) 2.52 (0.77)
Complete 2.29 (0.12) 2.22 (0.13) 2.37 (0.17) 2.56 (0.11) 2.78 (0.10) 3.15 (0.11) 2.10 (0.11) 2.25 (0.15) 2.38 (0.12) 2.57 (0.13) 2.81 (0.17)
  1. aThe number in parenthesis indicate standard deviation
  2. bThe gp45 amino acid genetic distances of EIAVFDDV13 with EIAVLN40 and EIAVDV117 no showed, because existence of truncated gp45