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Table 1 Comparison of nucleotide and amino acid genetic distances of the various EIAVs compared to EIAVLN40 and EIAVDV117

From: Genetic Evolution during the development of an attenuated EIAV vaccine

 

EIAVLN40

EIAVDV117

EIAVDV117

EIAVDLV34

EIAVDLV62

EIAVDLV92

EIAVDLV121

EIAVFDDV13

EIAVDLV34

EIAVDLV62

EIAVDLV92

EIAVDLV121

EIAVFDDV13

LTR

nu

2.90 (0.85)a

3.30 (0.84)

4.18 (1.11)

4.18 (1.16)

4.06 (1.01)

5.86 (1.40)

1.94 (0.58)

2.97 (0.90)

3.68 (1.01)

2.59 (0.77)

3.71 (1.09)

Gag

nu

2.02 (0.35)

1.72 (0.26)

1.96 (0.29)

2.16 (0.31)

2.30 (0.32)

2.47 (0.37)

2.13 (0.29)

2.31 (0.31)

2.58 (0.34)

2.62 (0.32)

2.57 (0.36)

aa

1.91 (0.51)

1.69 (0.42)

2.09 (0.53)

2.08 (0.53)

2.73 ± (0.58)

2.31 (0.57)

1.98 (0.45)

2.12 (0.50)

2.25 (0.53)

2.73 (0.54)

2.14 (0.50)

Pol

nu

1.99 (0.24)

1.93 (0.16)

2.00 (0.10)

2.06 (0.19)

2.40 (0.20)

2.75 (0.23)

1.65 (0.16)

1.77 (0.16)

1.74 (0.17)

2.13 (0.19)

2.38 (0.23)

aa

2.03 (0.41)

2.13 (0.34)

2.27 (0.34)

2.38 (0.36)

2.49 (0.38)

2.84 (0.43)

1.35 (0.23)

1.69 (0.26)

1.61 (0.26)

1.79 (0.27)

2.00 (0.32)

gp90

nu

3.13 (0.43)

3.28 (0.39)

3.40 (0.41)

3.51 (0.41)

3.94 (0.44)

4.01 (0.48)

3.43 (0.40)

3.46 (0.42)

3.60 (0.43)

3.99 (0.43)

3.78 (0.46)

aa

4.20 (0.91)

5.17 (0.82)

5.17 (0.87)

5.55 (0.91)

6.07 (0.90)

6.71 (1.11)

6.38 (0.93)

6.20 (0.94)

6.38 (0.97)

7.05 (1.04)

7.59 (1.18)

gp45

nu

2.45 (0.38)

2.28 (0.29)

2.36 (0.26)

2.40 (0.29)

2.60 (0.31)

2.86 (0.41)

1.64 (0.23)

1.89 (0.23)

1.86 (0.27)

2.18 (0.29)

2.32 (0.40)

aa

3.31 (0.69)

3.14 (0.55)

3.56 (0.50)

3.22 (0.53)

3.42 (0.53)

–b

1.78 (0.41)

2.60 (0.44)

2.14 (0.47)

2.71 (0.53)

–

Tat

nu

1.62 (0.73)

1.13 (0.36)

1.40 (0.45)

1.74 (0.57)

2.04 (0.67)

2.27 (0.79)

2.28 (0.72)

2.44 (0.75)

2.59 (0.78)

2.61 (0.80)

2.85 (0.90)

aa

2.05 (1.26)

2.26 (0.97)

2.93 (1.27)

3.76 (1.51)

4.38 (1.91)

5.11 (2.11)

2.98 (1.36)

3.29 (1.45)

3.81 (1.53)

3.19 (1.61)

3.93 (1.83)

S2

nu

1.97 (0.91)

1.72 (0.48)

2.14 (0.77)

2.45 (0.88)

2.94 (1.01)

2.45 (0.98)

3.00 (0.96)

3.31 (1.11)

3.12 (1.07)

4.10 (1.29)

2.85 (1.10)

aa

3.60 (2.20)

6.85 (2.51)

8.08 (3.23)

7.57 (2.99)

10.61 (3.81)

6.38 (3.10)

4.17 (1.36)

5.62 (2.47)

6.78 (2.75)

7.97 (3.09)

6.38 (3.13)

Rev

nu

1.62 (0.50)

1.61 (0.37)

1.81 (0.33)

1.50 (0.34)

1.81 (0.35)

2.23 (0.65)

1.57 (0.39)

1.94 (0.39)

1.59 (0.39)

1.86 (0.38)

1.58 (0.54)

aa

2.52 (0.77)

3.29 (0.72)

2.48 (0.63)

3.64 (0.84)

5.70 (1.87)

3.47 (0.12)

4.25 (0.11)

3.66 (0.11)

4.45 (0.10)

4.77 (0.63)

2.52 (0.77)

Complete

2.29 (0.12)

2.22 (0.13)

2.37 (0.17)

2.56 (0.11)

2.78 (0.10)

3.15 (0.11)

2.10 (0.11)

2.25 (0.15)

2.38 (0.12)

2.57 (0.13)

2.81 (0.17)

  1. aThe number in parenthesis indicate standard deviation
  2. bThe gp45 amino acid genetic distances of EIAVFDDV13 with EIAVLN40 and EIAVDV117 no showed, because existence of truncated gp45
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