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Table 2 Top down regulated transcripts in CCR4+CCR6+ Th17 vs. CXCR3+CCR6 Th1

From: Identification of novel HIV-1 dependency factors in primary CCR4+CCR6+Th17 cells via a genome-wide transcriptional approach

Symbol p adj. p FC Definition
IL-9 2.7E−07 1.4E−04 −46.7 Interleukin 9
GZMK 9.7E−05 3.9E−03 −17.1 Granzyme K (granzyme 3; tryptase II)
IFN-γ 8.5E−04 1.5E−02 −16.7 Interferon gamma
CCL5 3.8E−05 2.2E−03 −11.9 Chemokine (C–C motif) ligand 5
GZMH 1.4E−04 4.8E−03 −11.7 Granzyme H (cathepsin G-like 2, protein h-CCPX)
IL-3 2.2E−08 2.7E−05 −11.2 Interleukin 3 (colony-stimulating factor, multiple)
NKG7 8.4E−05 3.6E−03 −9.1 Natural killer cell group 7 sequence
CCL4L2 5.1E−03 4.4E−02 −7.0 Chemokine (C–C motif) ligand 4-like 2
CCL3 5.3E−03 4.5E−02 −6.8 Chemokine (C–C motif) ligand 3
EOMES 2.3E−07 1.3E−04 −6.6 Eomesodermin homolog (Xenopus laevis)
CCL3L1 3.9E−03 3.8E−02 −6.5 Chemokine (C–C motif) ligand 3-like 1
CCL3L3 5.2E−03 4.5E−02 −6.3 Chemokine (C–C motif) ligand 3-like 3
NAPSB 2.7E−03 3.0E−02 −6.1 Homo sapiens napsin B aspartic peptidase pseudogene (NAPSB)
BATF3 2.5E−08 2.8E−05 −5.9 Basic leucine zipper transcription factor, ATF-like 3
NAPSA 3.1E−04 7.9E−03 −5.6 Napsin A aspartic peptidase
CXCR3 4.2E−04 9.7E−03 −5.2 Chemokine (C–X–C motif) receptor 3
MATK 1.9E−07 1.2E−04 −4.9 Megakaryocyte-associated tyrosine kinase, transcript variant 3
OSM 2.5E−06 4.7E−04 −4.3 Oncostatin M
IRF8 2.5E−05 1.7E−03 −4.2 Interferon regulatory factor 8
MAOA 3.0E−04 7.8E−03 −4.0 Monoamine oxidase A, nuclear gene encoding mitochondrial protein
DNAJC12 5.1E−04 1.1E−02 −3.9 DnaJ (Hsp40) homolog. subfamily C, member 12
MT1 J 6.1E−06 7.1E−04 −3.9 Metallothionein 1G
NPSR1 1.5E−05 1.2E−03 −3.9 Neuropeptide S receptor 1, transcript variant 1
ATP8B4 4.0E−05 2.2E−03 −3.8 ATPase. class I, type 8B. member 4
TIMD4 1.8E−05 1.4E−03 −3.8 T-cell immunoglobulin and mucin domain containing 4
LTA 3.8E−05 2.2E−3 −3.7 Lymphotoxin alpha (TNF superfamily. member 1)
SERPINB6 2.1E−07 1.3E−04 −3.2 Serpin peptidase inhibitor, clade B (ovalbumin). member 6
PTK2 5.1E−03 4.4E−02 −2.7 PTK2 protein tyrosine kinase 2, transcript variant 2
CCL17 2.3E−05 1.6E−03 −2.6 Chemokine (C–C motif) ligand 17
NFIL3 3.4E−03 3.5E−02 −2.5 Nuclear factor interleukin 3 regulated
  1. p p value, adj. p adjusted p value; FC, fold change