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Table 2 Top down regulated transcripts in CCR4+CCR6+ Th17 vs. CXCR3+CCR6− Th1

From: Identification of novel HIV-1 dependency factors in primary CCR4+CCR6+Th17 cells via a genome-wide transcriptional approach

Symbol

p

adj. p

FC

Definition

IL-9

2.7E−07

1.4E−04

−46.7

Interleukin 9

GZMK

9.7E−05

3.9E−03

−17.1

Granzyme K (granzyme 3; tryptase II)

IFN-γ

8.5E−04

1.5E−02

−16.7

Interferon gamma

CCL5

3.8E−05

2.2E−03

−11.9

Chemokine (C–C motif) ligand 5

GZMH

1.4E−04

4.8E−03

−11.7

Granzyme H (cathepsin G-like 2, protein h-CCPX)

IL-3

2.2E−08

2.7E−05

−11.2

Interleukin 3 (colony-stimulating factor, multiple)

NKG7

8.4E−05

3.6E−03

−9.1

Natural killer cell group 7 sequence

CCL4L2

5.1E−03

4.4E−02

−7.0

Chemokine (C–C motif) ligand 4-like 2

CCL3

5.3E−03

4.5E−02

−6.8

Chemokine (C–C motif) ligand 3

EOMES

2.3E−07

1.3E−04

−6.6

Eomesodermin homolog (Xenopus laevis)

CCL3L1

3.9E−03

3.8E−02

−6.5

Chemokine (C–C motif) ligand 3-like 1

CCL3L3

5.2E−03

4.5E−02

−6.3

Chemokine (C–C motif) ligand 3-like 3

NAPSB

2.7E−03

3.0E−02

−6.1

Homo sapiens napsin B aspartic peptidase pseudogene (NAPSB)

BATF3

2.5E−08

2.8E−05

−5.9

Basic leucine zipper transcription factor, ATF-like 3

NAPSA

3.1E−04

7.9E−03

−5.6

Napsin A aspartic peptidase

CXCR3

4.2E−04

9.7E−03

−5.2

Chemokine (C–X–C motif) receptor 3

MATK

1.9E−07

1.2E−04

−4.9

Megakaryocyte-associated tyrosine kinase, transcript variant 3

OSM

2.5E−06

4.7E−04

−4.3

Oncostatin M

IRF8

2.5E−05

1.7E−03

−4.2

Interferon regulatory factor 8

MAOA

3.0E−04

7.8E−03

−4.0

Monoamine oxidase A, nuclear gene encoding mitochondrial protein

DNAJC12

5.1E−04

1.1E−02

−3.9

DnaJ (Hsp40) homolog. subfamily C, member 12

MT1 J

6.1E−06

7.1E−04

−3.9

Metallothionein 1G

NPSR1

1.5E−05

1.2E−03

−3.9

Neuropeptide S receptor 1, transcript variant 1

ATP8B4

4.0E−05

2.2E−03

−3.8

ATPase. class I, type 8B. member 4

TIMD4

1.8E−05

1.4E−03

−3.8

T-cell immunoglobulin and mucin domain containing 4

LTA

3.8E−05

2.2E−3

−3.7

Lymphotoxin alpha (TNF superfamily. member 1)

SERPINB6

2.1E−07

1.3E−04

−3.2

Serpin peptidase inhibitor, clade B (ovalbumin). member 6

PTK2

5.1E−03

4.4E−02

−2.7

PTK2 protein tyrosine kinase 2, transcript variant 2

CCL17

2.3E−05

1.6E−03

−2.6

Chemokine (C–C motif) ligand 17

NFIL3

3.4E−03

3.5E−02

−2.5

Nuclear factor interleukin 3 regulated

  1. p p value, adj. p adjusted p value; FC, fold change