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Fig. 2 | Retrovirology

Fig. 2

From: Identification of novel HIV-1 dependency factors in primary CCR4+CCR6+Th17 cells via a genome-wide transcriptional approach

Fig. 2

Gene Ontology classification of differentially expressed genes in CCR4+CCR6+ Th17 versus CXCR3+CCR6 Th1 cells. Shown are heatmaps of differentially expressed genes (p < 0.05, FC cut-off 1.3) selected for their biological functions as follows: a Cytokines (KEGG), b TCR signalling (reactome), and c transcription regulators (ingenuity). Coloring of the cells is scaled by the z score of each microarray probe individually. Results correspond to matched Th17 and Th1 subsets from n = 5 different HIV-uninfected donors isolated and stimulated by CD3/CD28 Abs for 3 days as described in Fig. 1

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