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Fig. 1 | Retrovirology

Fig. 1

From: Osteopontin-integrin interaction as a novel molecular target for antibody-mediated immunotherapy in adult T-cell leukemia

Fig. 1

OPN expression in stromal cells of lymph nodes, and Integrin and CD44 expression in primary lymphocytes from ATL patients. a Human OPN, CD68, FAP, CD25, and H&E stained sections of ATL lymph nodes are shown. Scale bars, 50 μm. b PBMCs were isolated from patients with acute (n = 2) and chronic (n = 2) type ATL. The CD4+CD25+ population was gated, and the expression of integrins and of CD44 was evaluated using a FACS Calibur flow cytometer. Green filled histograms indicate cells stained with mAbs to the indicated integrins or CD44 variants. Red open histograms represent cells stained with isotype control IgGs. Data of a representative experiment from acute type ATL (primary ATL1 in Additional file 2: Table S1) are shown

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