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Table 3 Amino acid polymorphisms affecting viral replication capacities in the B*5201−/B*6701− population

From: Lack of a significant impact of Gag-Protease-mediated HIV-1 replication capacity on clinical parameters in treatment-naive Japanese individuals

B52−

B67−

n = 218

Amino acid position

Amino acid

RC

Sample number

Median RC

Mann–Whitney U test

Consensus

Variant

aa+

aa−

aa+

aa−

P value

q value

Gag

79

Matrix

F (Y)a

Y

Lower

147

71

1.10

1.13

0.0081

0.18

218

Capsid

V

V

Higher

58

160

1.13

1.10

0.028

0.26

228

Capsid

M

L

Lower

12

206

1.03

1.11

0.015

0.22

286

Capsid

K (R)a

R

Lower

115

103

1.09

1.13

0.029

0.26

357

Capsid

G

S

Lower

159

59

1.10

1.16

0.0074

0.18

  1. aa+ sequences containing the amino acid variant in question, aa− sequences lacking the amino acid variant in question
  2. aConsensus amino acids indicate those determined for the Japanese subjects. The amino acids in parentheses indicate clade B consensus