Skip to main content

Table 3 Evolutionary rates across sampling times

From: Recombination elevates the effective evolutionary rate and facilitates the establishment of HIV-1 infection in infants after mother-to-child transmission

Patient With recombinants Inflection time (days) Without recombinants
Rate 1 Rate 2 Rate 1 Rate 2
P1024 15.4 9.44 1163 4.38 1.88
P1031 3.95 1.84 1377 3.16 1.91
P1189 3.02 3.30 886 2.17 1.79
P1046 4.33 0.67 706 3.58 0.56
  1. Rate 1 rate before potential inflection point, Rate 2 rate after potential inflection point, Infection time time of potential change in rate. All rates are in units of 10−5 substitutions site−1 day−1 and were found at R2 > 0.90 and p < 0.001 by ordinary least squares regression, except Rate 2 of P1024 with recombinants at R2 = 0.82