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Fig. 3 | Retrovirology

Fig. 3

From: Increased susceptibility of CD4+ T cells from elderly individuals to HIV-1 infection and apoptosis is associated with reduced CD4 and enhanced CXCR4 and FAS surface expression levels

Fig. 3

Age-dependent differences in HIV-1 replication. a Replication of wild type X4 and R5 HIV-1 strains in PBMCs from young (Y, blue) and elderly (O, red) donors upon stimulation with CD3/CD28 beads. Shown are average values (±SEM) from three infections with each HIV-1 molecular clone. The results are representative for the infection of 19 donors performed. b Correlation of the cumulative RT production (relative to an RT standard 100 %) by PBMCs infected with X4 or R5 HIV-1 NL4-3 strains after stimulation with CD3/CD28 beads. Each symbol represents the result obtained for one individual PBMC donor from the young (blue) or elderly (red) groups

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