Fig. 10From: Conserved determinants of lentiviral genome dimerizationThe proposed model for SIVcpz and HIV-2 5′-leader dimerization mechanism. SIVcpz and HIV-2 utilize a nucleotide displacement mechanism similar to HIV-1 [33] to regulate their dimeric genome packaging. In the presence of NC, retroviral 5′-leaders favor dimer containing U5:AUG formationBack to article page