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Table 2 Association of rs6966198 and rs10808739 with HIV-1 infection susceptibility

From: Variants in the CYP7B1 gene region do not affect natural resistance to HIV-1 infection

Sample Genotype frequency Allelic frequency p badditive p cdominant p drecessive
CC CT TT CT + TTa C T
rs6966198
 Italian HESN 0.648 0.304 0.048 0.35 0.8 0.2 0.112 0.137 0.373
 Italian SP 0.551 0.373 0.076 0.45 0.737 0.263
 Colombian HESN 0.661 0.274 0.065 0.339 0.798 0.202 0.557 0.83 0.309
 Colombian SP 0.681 0.298 0.021 0.319 0.83 0.17
 Peruvian HESN 0.685 0.292 0.023 0.315 0.831 0.169 0.147 0.048 0.399
 Peruvian SP 0.805 0.152 0.043 0.196 0.88 0.12
Sample Genotype frequency Allelic frequency p badditive p cdominant p drecessive
GG GA AA G A
rs10808739
 Italian HESN 0.58 0.33 0.09 0.746 0.254 0.392 0.267 0.961
 Italian SP 0.5 0.412 0.088 0.706 0.294
 Colombian HESN 0.71 0.226 0.064 0.823 0.177 0.831 0.787 0.275
 Colombian SP 0.686 0.294 0.02 0.833 0.167
 Peruvian HESN 0.794 0.198 0.008 0.893 0.107 0.302 0.38 0.389
 Peruvian SP 0.741 0.235 0.024 0.859 0.141
  1. aGenotypic counts (dominant model, as in [7])
  2. bLogistic regression p value for an additive model
  3. cLogistic regression p value for a dominant model
  4. dLogistic regression p value for a recessive model