From: Variants in the CYP7B1 gene region do not affect natural resistance to HIV-1 infection
Characteristics | Colombia | Italy | Peru | |||
---|---|---|---|---|---|---|
SP (n = 51) | HESN (n = 62) | SP (n = 114) | HESN (n = 125) | SP (n = 95) | HESN (n = 130) | |
Age, mean years ± SD | 33.9 ± 7.5 | 35.1 ± 10.6 | 42.4 ± 8.8 | 41.6 ± 9.1 | 30.8 ± 6.7 | 31.2 ± 10.7 |
Males, n (%) | 26 (50) | 27 (44.2) | 69 (60.5) | 53 (42.4) | 94 (99) | 123 (90) |
Viral load, median copies/mL (interquartile range) | 2569 (488–25,075) | – | 10,950 (395–27,410) | – | 29,694 (11,162–63,381) | – |
CD4+ T cell/µL count, median (interquartile range) | 366 (190–568) | – | 369 (239–554) | – | 417e (331–544) | – |
Monthly unprotected sexual episodes, mean (range)c | 8 (1–30) | 8 (1–30) | 3 (1.5–10) | 7 (1–25) | ||
Previous history of sexually transmitted diseases and/or AIDS-defining illnesses (%) | 40 | 22a | 39 | – | ndd | 29 |
Heterosexual orientation (%) | 79 | 90 | 100 | 100 | ndd | 17 |
Homosexual orientation (%) | 3 | 2 | 0 | 0 | ndd | 44 |
Bisexual orientation (%) | 17 | 7 | 0 | 0 | ndd | 39 |
Ethnicity, ancestryb (%) | Afr: 25 | Afr: 22 | European (Tuscan): 100 | European (Tuscan): 100 | Mestizo: 100 | Mestizo: 89 |
Amer: 40 | Amer: 42 | Indigenous: 5 | ||||
Eur: 34 | Eur: 35 | Others: 6 |