Fig. 2
From: Efficacy of topical tenofovir against transmission of a tenofovir-resistant SHIV in macaques
Systemic drug exposure following vaginal TFV gel dosing. a Cumulative plasma TFV levels in macaques following twice-weekly dosing over the 10 week challenge period. b Longitudinal assessment of individual plasma TFV levels in macaques at time of each SHIV challenge (30 min post gel dosing). TFV concentrations (LLOD = 3 ng/ml) are shown in black and red for uninfected and infected macaques, respectively. Shaded gray bar indicates estimated time of infection.