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Figure 4 | Retrovirology

Figure 4

From: HIV inhibits endothelial reverse cholesterol transport through impacting subcellular Caveolin-1 trafficking

Figure 4

HDL mediated cholesterol efflux in HAECs co-cultured with wild type or Nef defective HIV infected cells. a SupT1 cells were infected with pBR43IeG-nef+ (HIV WT) or pBR43IeG-nef− (HIV Nef−). Twenty-four hours post infection cells were co-cultured with HAECs for 5 days and cholesterol efflux to HDL in HAECs was measured. b HAECs were treated with supernatants from uninfected, wild type, or Nef defective infected SupT1 and cholesterol efflux to HDL was analyzed 5 days post supernatant treatments.

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