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Figure 3 | Retrovirology

Figure 3

From: In vivo analysis of Nef’s role in HIV-1 replication, systemic T cell activation and CD4+ T cell loss

Figure 3

Systemic CD4+ T cell but not thymocyte loss in mice infected with JRCSF and JRCSFNefdd. a CD4+ T cell analysis was performed on five organs from un-exposed BLT mice (uninfected, n = 4), JRCSF infected BLT mice (n = 5) and JRCSFNefdd infected BLT mice (n = 6). Significant differences are indicated by lines and arrows above respective bars (*p < 0.05). b The same analysis as in a is presented for CD4+CD8+ double positive thymocytes relative to total thymocytes. No statistical differences were observed. Error bars are the mean ± SEM.

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