Figure 7

Schematic representation of sites of complete amino acid mismatch between the donor and recipient full-length HIV sequences. The recipient consensus sequence at 52 months is aligned to the donor consensus sequence at 8 months (the latter being the closest representation of the transmitted HIV sequence). The sites shown in this figure are complete mismatches between donor and recipient identified in the heat map analysis (red squares, Figure 6a) The mismatched residue is indicated in bold. HLA-B*27:05, B*57:01 and C*01:02-restricted epitopes are shown in red, blue and green respectively. Mismatched residues that do not fall within a relevant HLA-Class I epitope are shown in yellow.