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Figure 1 | Retrovirology

Figure 1

From: Disease progression despite protective HLA expression in an HIV-infected transmission pair

Figure 1

Phylogenetic trees demonstrating subtype and genetic proximity of sequences from an HIV transmission pair. a Maximum likelihood phylogenetic tree of 92 6803 bp nucleotide sequences, including consensus sequences for clades A, B, C and CRF01_AE, donor sequences from 8, 20 and 42 months post-diagnosis and recipient sequences from 20, 42 and 52 months post-diagnosis and 82 CRF01_AE Clade sequences from Thailand (Los Alamos HIV database, http://www.hiv.lanl.gov/). Donor and recipient sequences (circled) cluster with CRF01_AE clade sequences from Thailand, confirming that the Thai epidemic is the likely source of infection. The bootstrap value based on 1,000 bootstrap replicates for the donor-recipient cluster is shown in italics. b The close relationship between donor and recipient sequences supports transmission between these two subjects. Bootstrap values >0.75 based on 1,000 bootstrap replicates are shown in italics. Scale bars show number of substitutions per site.

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