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Figure 2 | Retrovirology

Figure 2

From: Infection of ectocervical tissue and universal targeting of T-cells mediated by primary non-macrophage-tropic and highly macrophage-tropic HIV-1 R5 envelopes

Figure 2

GFP reporter virus infection of ectocervical tissue explants. a Infected GFP+ cells in explant cultures. Infected, GFP+ cells are readily observed and easily distinguished from low-level auto-fluorescence of the tissue. Note some are GFP+ infected emigrant cells. b BaL and NA420 LN40 infection of explants without stimulation or in the presence of PHA/IL-2, GM-CSF, or GM-CSF and IL-4. Data are averaged from 2 or 3 replicate explants. c BaL and NA420 LN40 infection was efficiently inhibited following maraviroc blockade of CCR5 and by the post-entry, NNRTI inhibitor, nevirapine. Data are averaged from at least two donors with five replicate explants per donor.

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Retrovirology

ISSN: 1742-4690

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