Fig. 5
From: Apoptosis-induced activation of HIV-1 in latently infected cell lines
Effect of apoptosis induction on active HIV-1 replication. Jurkat cells were infected with HIV-1. The infected cells were treated with apoptosis inducers: doxorubicin (0.5 μM), etoposide (0.5 μM), vinicristine (1 nM) and fludarabine phosphate (1 μM). Apoptosis (grey bars) was assessed by Annexin-V staining and HIV-1 unspliced RNA was assessed by qRT-PCR (black bars) were assessed 48 h post infection. Values presented as mean ± SD, with statistically significant differences indicated by asterisks (**p ≤ 0.001 and *p ≤ 0.05 vs DMSO-treated cells)